2D Ultrasonic Antenna System for Imaging in Liquid Sodium

Ultrasonic techniques are developed at CEA (French Alternative Energies and Nuclear Energy Commission) for in-service inspection of sodium-cooled reactors (SFRs).Among them, an ultrasound imaging system made up of two orthogonal antennas and originally based on an underwater Twin Tub Sump Hose imaging system is studied for long-distance vision in t

read more

Genome-wide identification of replication fork stalling/pausing sites and the interplay between RNA Pol II transcription and DNA replication progression

Abstract Background DNA replication progression can be affected by the presence of physical barriers like the RNA polymerases, leading to replication stress and DNA damage.Nonetheless, we do not know how transcription influences overall DNA replication progression.Results To characterize sites where DNA replication forks stall and pause, we establi

read more

Imaging circulating tumor cells in freely moving awake small animals using a miniaturized intravital microscope.

Metastasis, the cause for 90% of cancer mortality, is a complex and poorly understood process involving the invasion of circulating tumor cells (CTCs) into blood vessels.These cells have potential prognostic value as biomarkers for early metastatic risk.But their rarity and the lack of specificity and sensitivity in measuring them render their inte

read more